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Allergy & Intolerance Drug Sub-project

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Revision as of 14:01, 2 November 2016 by Jlyle (talk | contribs) (→‎Minutes)
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Purpose

Produce a list of unique substances and multiple substance medications used in allergy & intolerance lists, ordered by frequency of incidence. This list will support the use of common elements for data capture and validation of data exchange. This list is not intended to prevent the recording of unusual substances where necessary, whether by code or text.

We would like to provide a set of standard coded identifiers for these substances. The codes for such a list would need to be free, readily available, and accepted for use by international stakeholders.

Note that the criterion is clinical use, not chemical specificity. I.e., if all we know is that the patient reports an allergy to "fish," that's what we can record. Similarly, if a patient has a reaction to percocet, and the clinician doesn't have evidence that supports identification of a specific ingredient, then "percocet" is what we know.

Goal

  • A list of substances ordered by frequency of incidence, with frequency ratios
  • Identifiers for these substances, using freely available standard identifiers

Plan

  • Confirm goals
  • Assess assets
  • Evaluate gaps
  • Fill gaps

Open questions

  1. Include substances only, or also null and negative values?
    1. Use is the criterion: include what is used. Agreed 10/19
  2. What's the best system for encoding?
    1. Maximal coverage of identified requirements.
      1. Or ability to add missing items
    2. Freely available, internationally
  3. How to encode - automated, manual? How do we confirm quality?
  4. Encode and then combine, or combine and then encode?
    1. Encoding first makes consolidation easier
    2. TBD
  5. How do we weight lists?
  6. Rank all substances from contributed lists, or only those to a chosen level (97%, 99%, etc.)?

Minutes

2 November 2016

19 October 2016