CG WG Call Notes leading to 2014 January WGM

Proposed Agenda

• Discuss the revised Project Scope Statement of CG Domain Information Model(s)
  • Tooling alternatives: plain UML editor, MDHT, FHIR
  • Modelling goal: harmonize the v3, v2, GTR and FHIR models into an agreed-upon DIM
  • Modelling approach:
    • develop a list of requirements (should actually be in the DAM)
    • compare the various models in light of the requirements
    • harmonize the various models so that:
      • the harmonized DIM accommodates the requirements
      • as much as possible, there is a minimal effort to adjust each model to the harmonized DIM
  • Initial comparison:
    • The overall GTR model is based on a document model (CDA), i.e., header and sections
    • The GTR structured data is based on the Clinical Genomics Statement, which is a specialization of the CDA Clinical Statement model
    • The FHIR GeneticAnalysis Resource has the class DnaAnalysisDiscreteSequenceVariation that bundles the finding with the interpretation - that has been the subject of ongoing discussions in the HL7 Clinical Genomics group and the conclusion was that it is important to treat the interpretation as a separate observation with its time stamp, method, performer etc., rather than an inherent & single attribute of the finding observation class. To that end, the GTR Clinical Genomics Statement has the interpretation in a separate class associated with the genomic observation.

• Need to submit the Cambridge WGM Meeting Minutes by the end of this week