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201801 Pharmacogenomics CDS

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Pharmacogenomics CDS

Submitting WG/Project/Implementer Group

Clinical Genomics WG

Justification

Proposed Track Lead

Bob Dolin (BDolin@Elimu.io)

See Connectathon_Track_Lead_Responsibilities

Expected participants

  • Elimu
  • Cerner
  • Children’s Mercy Hospital

Please contact track lead or post to CG list if you're interested in participating!

Roles

PGx CDS Service

PGx CDS Service will interact with EHR (via CDS Hooks), OMIC Data Store (for genomoic observations), and Terminology Server (for medication value sets).

OMIC Data Store

Will store genomic observations

EHR

Order entry of a medication triggers a “medication-prescribe” CDS hook which invokes the PGx CDS Service and provides it with a FHIR MedicationOrder instance. This FHIR MedicationOrder instance includes RxNorm code 197388 (azathioprine 50mg oral tablet) in MedicationOrder.medicationCodeableConcept.

Terminology Service

The PGx CDS Service will ping the terminology server to see if the ordered drug is in an “Actionable PGx Drug” value set.

Scenarios

Please see detailed storyboard: https://docs.google.com/document/d/1VqPrf6aaOB8RhSbAq2JYDxZYbDm-RT9DxA0u6-RxYo0/edit


Scenario Step 1 Name

Action:
Precondition:
Success Criteria:
Bonus point:


TestScript(s)

Security and Privacy Considerations